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and Gutteridge J

It is an aminoglycoside which exhibits bactericidal effects both by disrupting cell membranes and impairing protein synthesis through binding to the 16S rRNA in helix 44 (h44) near the A site of the 30S ribosomal subunit

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DM is defined as a heterogeneous group of metabolic disorders characterized by unusual hyperglycemia resulting from defects in insulin production and/or action [1]

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